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• Creatine is one of the most extensively researched supplements in sports science — over 1,000 peer-reviewed studies have examined its effects since the 1990s.
• About 95% of the body's creatine is stored in skeletal muscle; the other 5% is found in the brain, liver, and kidneys.
• Vegetarians and vegans have naturally lower muscle creatine stores because dietary creatine comes almost exclusively from meat and fish — making supplementation especially beneficial for them.